Mohamed Naguib - His Work and Influence
Inaugural
Mohamed Naguib Lecture
Recording
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Inaugural Donors
$5000 and above
Sorin Brull, MD, FCARCSI
Pam Flood, MD
Steve Shafer, MD
$1000 to $4999
Mark Dershwitz, MD
Talmage Egan, MD
Stuart Forman, MD
Joseph Foss, MD
Ken Johnson, MD
$500 to $999
Elise Hyman & Family
Hugo Vereecke, MD
Thomas Henthorn, MD
Jonathan Moss, MD, PhD
Elie Sarraf, MD
Under $500
Franklin Dexter, MD PhD
Mark Hocevar
Jennifer Margaret Hunter, MB, ChB PhD FRCA FCARCSI
George Kracke, PhD
James Philip, ME(E), MD
Jijun Xu, MD, PhD
ISAP 5th Annual Mohamed Naguib Lecture
October 10, 2025
Guy Weinberg, MD
Guy Weinberg, MD will be present the 2025 Mohamed Naguib Lecture at the ISAP 2025 Annual Meeting on October 10, 2025. Dr. Weinberg is a Professor at the Department of Anesthesiology, University of Illinois - College of Medicine, Chicago, Illinois
Dr. Weinberg is best known for the discovery that infusing lipid emulsion (ILE) can attenuate or reverse local anesthetic systemic toxicity, LAST. This approach is now considered a standard of care for treating LAST. Dr. Weinberg initially trained at UCSF, receiving board certification in Internal Medicine and Medical Genetics before doing a research fellowship at the NIH. He then switched gears and careers to do a residency in Anesthesiology at UVA Charlottesville where he learned regional anesthesia working under Harold Carron and John Rowlingson. After moving to Chicago, where he worked at Michael Reese Hospital and the University of Illinois, a single peculiar clinical event led to studies of novel molecular targets of local anesthetics and eventually to the discovery that ILE can reduce related toxicity. His lab at the Jesse Brown VA focused on this phenomenon and its underlying mechanisms for more than 20 years. Dr. Weinberg chaired the ASRA working group on LAST for more than a decade and helped form the first advisories for treating LAST. He now co-hosts an annual workshop in Telluride, CO where leading scientists from around the world meet to discuss data on a set of genes, YAP and WWTR1 (TAZ), that contribute to many types of cancer.
Generous support provided by Senzime Corporation
Dr. Daniel Rotroff, PhD, MSPH, will present the 2024 Mohamed Naguib Lecture on the topic of: Carrying on What Dr. Naguib Started: Chemotherapy Induced Peripheral Neuropathy.
Daniel Rotroff, PhD, MSPH, is Director, for the Center for Quantitative Metabolic Research, at the Cleveland Clinic, Cleveland, OH, USA.
About Dr. Mohamed Naguib
International Society of Anaesthetic Pharmacology (ISAP), established the Mohamed Naguib Lecture to honor the late Dr. Mohamed Naguib. Dr. Naguib had a distinguished career in the field of anesthesiology and was a long supporter of ISAP, serving as President of the society. He made significant contributions to the scientific foundation and clinical applications of neuromuscular monitoring. This named lecture is given at each ISAP Annual Meeting.
ISAP has established a fund to endow the Mohamed Naguib Lecture and donations may be made at isaponline.org.ISAP has established a fund to endow the Mohamed Naguib Lecture and donations may be made at isaponline.org.
In the world of clinical pharmacology, Dr. Naguib was a renaissance man. As a man of many talents, his influential work has provided direction in many spheres of investigation and discovery. He made significant contributions to the scientific foundation and clinical applications of neuromuscular monitoring. He formed and led a coalition of thought leaders to prepare and disseminate expert consensus guidelines on neuromuscular monitoring. He had substantial interest in the mechanisms of and treatment for neuropathic pain. He led a laboratory that created molecules to treat neuropathic pain. At the time of his passing, he was a principal investigator on NIH funded multi-center observational study focused on the discovery and validation of a biomarker signature for chemotherapy induced peripheral neuropathic pain. He was the co-founder of a company that is developing a novel therapy for neuropathic pain and Alzheimer’s disease based on his research on the mechanisms of neuroinflammation. For each of these activities, he created a wake of opportunities for many that continue to have a vibrant and productive future. He was a prolific writer. He was the principal author or co-author of 130 peer-reviewed journal articles, 25 book chapters (including the premier Miller’s Textbook of Anesthesia) and 150 abstracts.
Dr. Naguib was graduated from the Cairo University, College of Medicine, in 1976 and finished his anesthesia residency in 1981. He served as a Post-Doctoral Research Fellow in the Department of Anesthesiology, University of California, San Diego, California. In 1992 he joined the Department of Anesthesia at the College of Medicine, King Saud University. In 1998 he joined the University of Texas MD Anderson Cancer Center in Houston. His last position was the 2010 appointed as Professor of Anesthesiology, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University.